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How does Fildena 100 work in the body?

Fildena 100 is a medication primarily used to treat erectile dysfunction in men by enhancing blood flow to the penis during sexual stimulation. The active ingredient in Fildena 100, sildenafil citrate, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the body. This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP), a chemical that relaxes smooth muscles, dilates blood vessels, and improves blood flow to the penis.

When a man is sexually aroused, nitric oxide is released in the penis, which stimulates the production of cGMP. An adequate amount of cGMP is essential for the relaxation of smooth muscles and vasodilation, allowing blood to flow into the penile tissues, leading to an erection. However, PDE5 can break down cGMP, leading to a decrease in blood flow and erectile dysfunction.

By blocking the action of PDE5, sildenafil citrate helps maintain higher levels of cGMP in the penis, promoting prolonged vasodilation and improved blood flow. This results in a firm and sustainable erection suitable for sexual intercourse. It is important to note that Fildena 100 does not cause an automatic erection; sexual stimulation is still required to activate the release of nitric oxide in the body.

In conclusion, Fildena 100 facilitates erectile function by regulating the levels of cGMP through PDE5 inhibition, ultimately improving blood circulation to the penis. This mechanism of action has made Fildena 100 a widely used and effective treatment for erectile dysfunction in men.